People often ask if stimulating their brain on a regular basis makes any positive difference. Studies of Einstein's brain structure may shed some light on such questions. Some of Einstein's abilities were probably hereditary. But the type of research he did required intense study, and such concentrated effort can apparently alter the brain physically. Researchers at UCLA, Laboratory of Neuroimaging, reported in the journal Neuroimage that regular meditation, for example, can increase the size of brain areas that regulate emotion. Interestingly enough, a curious knob-like feature that was identified in pictures of Einstein's motor cortex might be a result of his early musical training. The feature resembled a structure detected in neural studies of experienced pianists and violinists, thought to be caused by hand exercises.