Old Year's Day

Well, it has arrived, the last day in the year 2013, also known as New Year's Eve or Saint Sylvester's Day. It ushers in the next, new year. Growing up I always thought it strange that it didn't happen at the same time around the world. For example, the island nations of Samoa and Kiribati are the first to let the old year slip away while Honolulu, Hawaii is among the last places. What are doing to say farewell to this year? The way people do this can be all over the board from going to bed early and sleeping the new year in, to celebrating until midnight, or even staying up into the wee small hours of the new year. My preference is to low-key it with a few close friends, thinking about what happened over the last 12 months and imagining what may occur over the upcoming 12 months. Whatever you do, be happy and grateful. My brain is, for my having lived through another year.

 

 

 

"Molecular" Communication

There’s electromagnetic communication (children and pets are reportedly very sensitive to this); and pheromone communication within the same species (insects for long-range signaling, rats, humans); and now there is new information about molecular communication. This method will not replace electromagnetic waves, which transmit the bulk of data in the modern world, but there are some areas where conventional communications systems are not particularly well-adapted. These areas can include pipelines, tunnels, deep underground structures, and inside the human body. Researchers at the University of Warwick in the UK and the York University in Canada have developed the capability to transform any generic message into binary signals, which in turn is 'programmed' into evaporated alcohol molecules to demonstrate the potential of molecular communications. Dr. Weisi Guo, University of Warwick, said: "Imagine sending a detailed message using perfume―it sounds like something from a spy thriller novel, but in reality it is an incredibly simple way to communicate.” Their results are published in the open access journal PLOS ONE. 

http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0082935

DNA and a Hidden Code?

DNA has been referred to as the “mystery substance” that impacts who you are (in comparison to your biological relatives). Scientists at the University of Washington believe they have discovered that DNA is really an incredibly powerful information storage device and much more complex than originally believed. In fact, they believe it contains a second hidden code. The genetic code uses a 64-letter alphabet called codons. Some codons, “duons,” can have two meanings, one related to protein sequence, and one related to gene control. This means that “many DNA changes that appear to alter protein sequences may actually cause disease by disrupting gene control programs or even both mechanisms simultaneously,” according to a researcher.  It appears that a secret language in the DNA itself may be a contributor to how "nature" is expressed. Sounds a bit like Dan Brown’s Da Vinci Code! No wonder every individual, every brain, is unique.

• A. B. Stergachis et al., Exonic Transcription Factor Binding Directs Codon Choice and Affects Protein Evolution, Science, 2013, DOI: 10.1126/science.1243490
• Robert J. Weatheritt, M. Madan Babu, The Hidden Codes That Shape Protein Evolution, Science, 2013, DOI: 10.1126/science.1248425

Sleep Deprivation #7

According to an article published in Nature Neuroscience, studies at the University of California-Berkeley have linked adequate deep sleep to a good memory. Researchers gave 18 college-aged participants and 15 senior participants a series of memory tests, monitored participants' sleep using an electgroencephalogram (EEG) machine, and then tests the participants next morning on the memory tests. Before going to sleep all the participants scored similarly on the test. It was a different story the next morning, however. The older participants were more than 50% less accurate on the memory tests after sleeping. Study co-author Bryce Mander said that analysis showed the differences were not due to changes in memory capacity but to differences in sleep quality. The EEG readings revealed that the seniors got only about 1/4th as much deep sleep as the younger participants. Researchers concluded that the forgetfulness that is often linked with aging may actually be caused by a lack of deep sleep. The differences in memory was attributed to the amount of high-quality deep sleep that the two groups of participants were able to achieve. You might want to pay close attention to this as "sleep" often seems to suffer during holiday seasons . . .

Boxing Day

Growing up in a British Commonwealth Country, we always celebrated boxing day. It was a federal holiday in Canada, although the exact etymology of the term "boxing day" is unclear. A ‘Christmas Box’ in Britain was a common name for a Christmas present. In older English tradition, employers expected their servants to “serve” on Christmas day. The servants were allowed to take off December 26^th however, to visit their own families. The employers would give each servant a Christmas box containing, bonuses and gifts, and often leftover food items. It may also be connected to the “Feast of Stephen.” Donation boxes were placed in churches where parishioners deposited coins for the poor. These boxes were opened and the contents distributed on December 26, the Feast of St. Stephen. During the late 18^th century, lords and ladies of the manor would “box up” food and gift items and deliver then to tenants who worked and lived on their lands. When I moved to the United States it seemed that few if any had heard of Boxing Day. I still give some gifts on Boxing Day in remembrance of a cultural difference from my native land. 

Happy December 25th!

Today is a widely observed by millions around the world. For some it is an annual commemoration of the birth of the Christ child. For others it is a civil holiday, celebrated by an increasing number of non-Christians. Some of you may be celebrating in traditional style. Others of you may not. Many have the day off work. Other must be at work. Some are able to be with family. Again, others are not. As a child growing up in Canada, we would gather ‘round the radio to hear the King’s Speech (or the Queen’s Speech), after which we would open presents, eat a special dinner served on dishes reserved for special occasions, and have food treats such as Halva and fruit cake. Often the afternoon would again find us grouped around the radio listening to “A Christmas Carol” or Perry Como. It was a “must” to think of at least one thing for which we were grateful. It turned into a tradition that I still honor. Take a moment today to think of at least one thing for which you are grateful. You may not have everything you would wish for; you do have something for which to be grateful. Happiness is a choice. Today, hang out with happy people because happiness seems to rub off on each other. Whatever your style, whatever you do, whomever you are with, my wish is that you have a happy, rewarding, and fulfilling day. I am low-keying it myself, surrounded by a very small circle of family-of-choice…

Memories . . .

“‘Twas the night before Christmas, when all thru the house, not a creature was stirring, not even a mouse …” Do you recall that verse attributed to Clement Clarke Moore? I’m quite sure there was usually at least one mouse in our basement. Heaven knows my mother was always putting out mouse traps. In my childhood home, it was always made very clear that Santa Clause was a concept, not a real person, albeit that the concept was likely based on a real person. Nevertheless, that never seemed to diminish the magic, especially during the years we lived amidst a great deal of snow! Relatives on both sides of my family tree often went to late evening or mid-night community or church service, listening to the music of the season, drinking in the colorful lights and candles, and hearing once again the familiar stories and poems. It was also a time of reflection. Every year some would be missing from the group, their having died during the past twelve months. Sometimes we would put a place-card at the table in their honor or at least reminisce about them, being reminded that we can choose to carry each in our hearts and minds. Good memories. “…and to all a good night.” 

Infrasounds, #3

The roar of a tiger contains audible sounds and infrasounds of 18 Hz and lower—which can penetrate solid objects like walls and even pass through mountains. Its prey feels the infrasounds in addition to the threatening roar—usually the last thing the victim hears—which can reach 114 decibels a few feet away (25 times as loud as a gas lawn mower). Humans can feel the tiger’s roar, a sensation that can cause momentary paralysis, even in trainers who have worked with tigers for years. Infrasounds have been linked to spooky events, as well. Mysteriously snuffed out candles, weird sensations and shivers down the spine may be due to infrasound and may produce a range of bizarre effects in humans including anxiety, sorrow, chills, feeling uneasy, feelings of revulsion or fear, or making people feel vaguely odd or that events are occurring. It’s the holiday season. Find yourself an organ concert and listen to the music of the season. Revel in the infrasounds from the very low pedal pipes on a huge pipe organ! Pay attention to what you "feel" versus what you "hear."

Infrasounds, #2

Infrasounds are prevalent among creatures in nature, too. Hippopotamuses, alligators, and giraffes reportedly use infrasound to communicate over distances—perhaps hundreds of miles in the case of whales and elephants. Sumatran Rhinoceros produce infrasounds as low as 3 Hz with similarities to the song of the humpback whale. Recent research by Jon Hagstrum of the US Geological Survey suggests that homing pigeons use low frequency infrasound to navigate. Elephants trumpet at 15-35 Hz and as loud as 117 decibels, the sound traveling distances up to six miles and used to coordinate the movement of herds and allow mating elephants to find each other. Elephants also produce infrasound waves that travel through solid ground and are sensed by other herds using their feet, although separated by hundreds of miles. Typically, you can feel and hear your cat purr because the purr of felines is reported to cover a range of 20 Hz to 50 Hz. And then there is the roar of the tiger. More on that tomorrow.

Infrasounds, #1

You probably already know that the normal lower limit of adult human hearing is 20 Hz (Hertz) or cycles per second. Enter Infrasounds: low-frequency sounds, lower than the normal limit of human hearing, which have a very long wave that goes between particles and molecules rather than bouncing off of them. High-intensity infrasounds extend in the megahertz range and well beyond but their frequency level is below 20 Hz so you can feel but not hear them. Sometimes you can hear part of the sound and feel the rest. Sometimes you can only feel the sound. Infrasound can be generated by sonic booms, explosions (both chemical and nuclear), machinery such as diesel engines, trains, planes flying overhead, large-scale subwoofer loudspeakers (e.g., rotary woofers), wind turbines, specially designed mechanical transducers such as industrial vibration tables, and very low pedal pipes on a huge pipe organ. Infrasounds can result naturally from surf, avalanches, earthquakes, volcanoes, waterfalls, calving of icebergs, meteors, lightning, severe weather, and etc.

Long QT Syndrome

Speaking of loud sounds and the potentially deleterious impact they can have on brain and body, have you heard of the Long QT Syndrome? It is a very rare condition in which the electrical recovery of the heart after each beat takes longer than usual, the rhythm becomes abnormal, and insufficient blood is pumped to the brain. Sometimes the individuals recover; sometimes they do not. Estimates are that Long QT Syndrome contributes to about 3,000 deaths per year in the US. According to the Better Health Channel (see link below), this is a potentially life-threatening disorder. An event can be triggered by:

• Being startled by a loud noise, such as a horn, ringing telephone or alarm clock
• Exams, tests or other stressful situations
• Anger or crying
• Exercise.

There's often quite a bit of loud sounds during the holiday season. You might want to start carrying some ear plugs in your pocket. Use them to protect yourself.

 http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Long_QT_syndrome

Loud Sounds, Brain, and Heart

As a person with an auditory sensory preference, I’ve carried ear plugs with me for years, wearing them on airline flights, at concerts and rodeos, and you name it. The noise-cancelling music plugs I use, thanks to recommendations by a good friend, still allow me to “hear” but take the sound level down about 20 decibels. Research has validated my choice. Long-term exposure to noise is believed to raises the levels of stress hormones such as cortisol, adrenaline, and noradrenaline in the body. And, high levels of stress hormones have been linked to high blood pressure, heart failure, strokes, and immune problems. A study published in the European Heart Journal reported that males exposed to prolonged noise had a 50% higher risk of heart attack; women almost 300% higher risk. Your choices can make a difference. Use ear plugs whenever possible in noisy situations. Keep the volume only as loud as you need it to hear clearly on cellphones and headphones. Select a less noisy restaurant or a walk in the park over one near a busy street. Spent a few minutes every day in silence, relaxing, and focusing on your breathing. Take care of your ears—and, by extension, your brain and your heart.

Plasticity Post Brain Injury

The brain is heavily interconnected with neuron pathways. According to life scientists from UCLA and Sydney Australia’s Garvan Institute of Medical Research, you can get from any neuron in the brain to any other neuron via about six synaptic connections. New research has revealed that when the hippocampus, the brain’s primary learning and memory center, is damaged, complex new neural circuits arise to compensate for the lost function. And these circuits can be some distance from the hippocampus. In the prefrontal cortex, for example. Their breakthrough discovery, the first demonstration of such neural-circuit plasticity, could potentially help scientists develop new treatments for Alzheimer’s disease, stroke, and other conditions involving damage to the brain.

Moriel Zelikowsky et al., Prefrontal microcircuit underlies contextual learning after hippocampal loss, Proceedings of the National Academy of Sciences, 2013, DOI: 10.1073/pnas.1301691110

Your Avatar

According to Wikipedia, an avatar (usually translated from Sanskrit as incarnation) is the graphical representation of the user or the user’s alter ego or character. It may take a three-dimensional form as in games or virtual worlds ... Studies at the University of Michigan showed that when people create and modify their virtual reality avatars, the hardships faced by their alter egos can influence how they perceive virtual environments. For example, Sangseok You, a doctoral student in the school of information at the University of Michigan, reported that participants who saw that a backpack was attached to an avatar that they had created overestimated the heights of virtual hills, just as people in real life tend to overestimate heights and distances while carrying extra weight. “You exert more of your agency through an avatar when you design it yourself," said S. Shyam Sundar, Distinguished Professor of Communications and co-director of the Media Effects Research Laboratory, Penn State, who worked with You. "Your identity mixes in with the identity of that avatar and, as a result, your visual perception of the virtual environment is colored by the physical resources of your avatar." The study may help trainers and game developers design virtual reality exercises and games that are more realistic and more immersive¾because "You are your avatar when it is customized."

http://news.psu.edu/story/275626/2013/05/02/research/bonding-your-virtual-self-may-alter-your-actual-perceptions

Measuring Em Energy of Brain Bleeding

UC Berkeley researchers have developed a device that uses wireless signals to provide real-time, non-invasive diagnoses of brain swelling or bleeding. The device’s diagnoses for the brain trauma patients in the study matched the results obtained from conventional computerized tomography (CT) scans. Because fluid conducts electricity differently than brain tissue, it is possible to measure changes in electromagnetic properties. The tests also revealed some insights into the aging brain. With increased age, the average electromagnetic transmission signature of a normal human brain changes and approaches that of younger patients with a severe medical condition of hematoma in the brain. For brain hematomas, internal bleeding causes the buildup of blood in specific regions of the brain. For brain edemas, on the other hand, swelling results from an increase in fluid in the tissue.

http://www.kurzweilai.net/wireless-signals-could-transform-brain-trauma-diagnostics?utm_source=KurzweilAI+Weekly+Newsletter&utm_campaign=bddc0d983d-UA-946742-1&utm_medium=email&utm_term=0_147a5a48c1-bddc0d983d-281999441

Brain Perception of Silhouettes

Some of you know that I enjoy showing brain-perception puzzles at some of my seminars (e.g., facial shapes hidden among the branches of a tree). Some brains see the tree first, others notice the faces first. Some brains see most of the faces; others don’t. The results of a new study by Jay Sanguinetti, a doctoral student at the University of Arizona, challenges currently accepted models, in place for a century, about how the brain processes visual information. He discovered that the brains perceives objects in everyday life that its owner may not be consciously aware of. He showed participants a set of black silhouettes. Some contained meaningful, real-world objects hidden in the white spaces on the outsides and some did not. Meantime, the brainwaves of the participants were being monitored with an electroencephalogram, or EEG, while they viewed the objects. Surprisingly, participants’ brainwaves showed that even if a person never consciously recognized the shapes on the outside of the image, their brains still processed those shapes to the level of understanding their meaning.

http://www.kurzweilai.net/does-your-brain-see-things-you-dont?utm_source=KurzweilAI+Weekly+Newsletter&utm_campaign=16b2dbd165-UA-946742-1&utm_medium=email&utm_term=0_147a5a48c1-16b2dbd165-281999441#!prettyPhoto

3D Neuron Model

According to Kurzweil News, the first 3D-printed neuron has been created by neuroscientist Gordon Shepherd of Yale University in collaboration with the Yale Center for Engineering Innovation and Design. “Brain microcircuits have a very complicated 3D architecture,” said Shepherd, a professor of neurobiology at the Yale School of Medicine and author of The Synaptic Organization of the Brain, a classic in the literature of neurobiology. It’s rather amazing to look at a picture of this plastic 3D-neuron replica, thousands of times larger than it is in real life, and know that there are millions and billions of them diligently working 24-7 to keep your brain and body going.

http://www.kurzweilai.net/first-3d-printed-model-of-a-neuron?utm_source=KurzweilAI+Weekly+Newsletter&utm_campaign=16b2dbd165-UA-946742-1&utm_medium=email&utm_term=0_147a5a48c1-16b2dbd165-281999441

Mentoring and Learning

Researchers from the Department of Psychology, University of British Columbia in Vancouver, Canada compared the potential impact on learning between groups of participants who either observed one teacher only or who observed five teachers. The participants were asked to learn new skills (digital photo editing and knot-tying) and then pass on those new skills to the next “generation” of participants. There were some interesting results. For example participants who were given greater access to teachers (role models) accumulated significantly more skill than those with less access to teachers. Within ten “generations,” each member of the group with multiple mentors had stronger skills than did participants who were limited to a single mentor. Those with greater access to teachers also retained their skills much longer than groups who began with less access to mentors, sustaining higher levels of “cultural knowledge” over multiple generations. According to the researchers, the study has important implications for several areas, from skills development and education to protecting endangered languages and cultural practices.
Michael Muthukrishna et al., Sociality influences cultural complexity, Proceedings of the Royal Academy: Biological Sciences, 2013, doi: 10.1098/rspb.2013.2511 (open access)

Stuttering and the Brain #2

Producing speech utilizes several portions of the human brain. It is believed that the Basal Ganglia actually controls speech. Wernicke’s area in the left temporal lobe tells you which word you want to say. Then Broca’s area in the left frontal lobe actually forms the word, while the Striatum times and initiates speech, coordinating the output with the mouth, tongue, and throat. Pretty complex. There is growing evidence that stuttering has a neurological base rather than an emotional base as has often been assumed. It may involve a miscommunication between speech centers in the brain (such as the striatum, a major input station of the brain’s basal ganglia system\) and the mouth and tongue. Work by Gerald A. Maguire MD of UC Irvine, reportedly has led him to believe that stuttering may involve bombardment of the striatum with too much dopamine (as opposed to Parkinson’s disease that involves a loss of dopamine to the striatum) and some medications are being trialed. You may find the CNN youtube clip interesting.

http://www.youtube.com/watch?v=tEitDTX2ZAo

Stuttering and the Brain #1

Speech is a terrifying complex process. No surprise that some brains have difficulty doing this smoothly. Remember the movie The King’s Speech? Most people have a least one friend who stutters or have heard about stutterers such as Winston Churchill or James Earl Jones. Although stuttering continues to be somewhat of a medical mystery, some interesting information is emerging. First, it is a physical condition whereby speech is interrupted, but only communicative speech to others. If you’re talking to yourself, apparently you don’t stutter. It may run in families, too. About 70% of stutterers show some familial tendency. While stress can exacerbate stuttering in someone who has the trait, it doesn’t cause it. This can make it tough on a child whose peers make fun of his or her speech difficulties. Excitement and passion about the topic under discussion can also increase the stutter. Most stuttering begins between the ages of two and five. Someone recently sent me a youtube of an interview with Annie Glenn, Astronaut John Glenn’s wife, related to her history of stuttering and the HCRI therapy that helped her reduce the incidence.

http://www.youtube.com/watch?v=UHCjVctuQ7g

Stiff-Person Syndrome Part 5 of 5

This year marks the 30^th anniversary of NORD and the Orphan Drug Act. Passed in 1983, the Orphan Drug Act was designed to stimulate the development of products to treat rare diseases and conditions. For drugs, a disease or condition is considered rare if it affects less than 200,000 persons in the United States. For medical devices, a disease or condition is considered rare when it occurs so infrequently in the US that there is no reasonable expectation that a medical device for such disease or condition will be developed without assistance. According to the National Institutes of Health, there are about 6,800 rare diseases and conditions. In total, nearly 30 million Americans (maybe one in ten) suffer from at least one rare disease; a rare disease such as Stiff-Person Syndrome or SPS. In February of 2014, Shane James is planning to run 28 marathons in 28 days in Run To Live Tasmania. Starting in Burnie, heading down the east coast to Hobart, then back up on the west coast and cruising back to Burnie, runners and riders alike are welcome to join the “28 in 28 run” for any distance they wish. Shane hopes to accomplish two specific goals by this endeavor: raise awareness of Stiff-Person Syndrome or SPS and other rare disorders and raise money for a couple of non-profit agencies:

USA:  NORD, the National Organization for Rare Disorders (www.rarediseases.org)

Australia: Steve Waugh Foundation (www.stevewaughfoundation.com.au)

Stiff-Person Syndrome Part 4 of 5

“How could running help people with SPS feel better?” is a common question. Your brain contains a sophisticated, internal pharmacy. Physical exercise triggers the brain’s own personal pharmacy to release a number of endogenous or internal chemicals that flood the brain and spinal cord. Endorphins, natural brain-body opiates, are more powerful than human-made exogenous (outside the body) substances. Adrenalin may be released by the challenge and exhilaration of running, which not only provides a boost of energy but also triggers the release of dopamine, the “feel-better” brain chemical. Other brain chemicals such as serotonin may be released as well. In combination, this cocktail of natural brain-body “medications” helps the individual feel better. Diagnosed with Stiff-Person Syndrome in 2007, this is what Shane James does when he runs. And yes, it helps him feel better. You, too, have your own internal pharmacy. Think of yourself as the pharmacist who releases drugs and other chemicals for use in your brain and body. You “release” these based on your lifestyle, behaviors, mindset, thoughts, and a whole host of other factors such as what you eat and drink and how much you sleep. . .

Stiff-Person Syndrome Part 3 of 5

Stiff-Person Syndrome, a very rare condition. So what is known about? Scientists don’t yet understand what causes SPS but research indicates that it is the result of an autoimmune response gone awry in the brain and spinal cord. It may begin very subtly during a period of emotional stress. SPS is often misdiagnosed as Parkinson’s disease, multiple sclerosis, fibromyalgia, psychosomatic illness, or anxiety and phobia. Studies have confirmed that it is typically characterized by a high titer of anti-GAD (glutamic acid decarboxylase) antibodies. While the absence of antibodies in the serum does not rule out SPS, the presence of anti-GAD autoantibodies strongly supports that diagnosis (99% specific by immunocytochemistry). What isn’t known for sure is whether the antibodies have a causative role or are the result of another process. Interestingly, SPS has not been described in members of the same family and there is no known genetic predisposition. Stiff-person syndrome is considered by many researchers to be a spectrum of disease ranging from the involvement of just one area of the body to a widespread, rapidly progressive form that also includes involvement of the brain stem and spinal cord.  Shane, a man I met on a recent airline flight to Australia, who has been diagnosed with SPS, is learning how to manage the pain through his own rehabilitation program. 

Stiff-Person Syndrome Part 2 of 5

Although the specific prevalence of Stiff-Person Syndrome or SPS is unknown, it may occur in fewer than 1 in 1,000,000 persons. It is sometimes referred to as an orphan disease, one of those conditions that occurs so rarely that there are insignificant funds available to support research. Largely as a result of donations, NORD or the National Organization for Rare Disorders awarded a small research grant for SPS in 2010. Likely involving an autoimmune process, there is no clear racial or ethnic predisposition, although the disease may be more common in women than in men. According to www.hopkinsmedicine.org, the ratio is two women for every man effected. Interestingly, SPS has not been described in members of the same family and there is no known genetic predisposition. The link below is to Shane's new website:  http://www.run-to-live.com/

Stiff-Person Syndrome, 1 of 5

Do you feel stiff from time to time? We all do! Not everyone has Stiff-Person Syndrome or SPS, however. No, it’s not a joke. SPS really does exist! Also known as stiff-man syndrome and Moersch-Woltman condition, reportedly it was described first by Moersch and Woltman at Mayo clinic in 1956. On a recent airline flight to Australia I sat next to Kati and her boyfriend Shane, who was diagnosed with Stiff-Person Syndrome in 2007. We chatted a bit about the impact SPS has had on his life and how he developed and embarked on his own rehabilitation program, which has kept him out of a wheelchair and that actually may have saved his life.  A very rare disease of the nervous system, SPS may begin very subtly during a period of emotional stress and likely involves an autoimmune process. SPS is characterized by progressively severe muscle stiffness typically in the spine and lower extremities. Most patients experience painful episodic muscle spasms that are triggered by sudden stimuli. Shane stumbled across the recognition that when he experienced muscle spasms, exercise helped reduce his pain. As you may imagine, that has changed the way he relates to and manages SPS.

Nelson Rolihlahla Mandela

Today we pause to reflect on the 96 years of Nelson Rolihlahla Mandela. I recall standing in the unbelievably small cell on Robben Island where Mandela spent so many solitary years. From the 17^th to the 20^th centuries, Robben Island served as a place of banishment, isolation and imprisonment. Today it is a World Heritage Site and museum, a poignant reminder  of the price paid for freedom. Looking toward shore from the island, I could glimpse Table Mountain in the distance. So near and yet so far. Although not much of a souvenir collector, I brought back two copies of the key to Mandela's prison cell: One for me and one for Dr. Sharlet Briggs. I agree. There likely will not be another Nelson Mandela, no other brain that could accomplish what he managed to accomplish and in the way he accomplished it. I have a favorite quote of his, also:  “It always seems impossible until it’s done.”

Gender and Map Reading, #2

Researchers at the University of Pennsylvania used a special brain-scanning technique called diffusion tensor imaging, which can measure the flow of water along a nerve pathway. According to Professor Verma, this technique established the level of connectivity between nearly 100 regions of the brain, creating a neural map of the brain called the “connectome.” It allows scientists to determine whether one area of the brain is physically connected to another area of the brain, which allows them to compare similarities and differences between two populations. Conclusions are that there are differences in the way nerves connect when comparing male brains with female brains. It appears that a type of hardwiring occurs during adolescence, a time when many of the so-called secondary sexual characteristics such as facial hair in men and breasts in women develop. Researchers believe that these hardwiring differences play an important role in understanding the reason males are generally better at spatial tasks involving muscle control, while females are generally better at verbal tasks involving memory and intutition.

Gender and Map Reading, #1

For several years now research studies related to gender differences have provided interesting tidbits on how male and female brains differ. For example, common wisdom has been that the male brain seems to be better at map reading. There are always exceptions because each brain is so individualized. Some women are better at map-reading than some men, but the generalization is in favor of the male brain. Women, on the other hand, appear to be better at recalling the content of conversations. A pioneering study at the University of Pennsylvania in Philadelphia has shown for the first time that the brains of men and women are wired up differently. Turns out that many of the connections in a typical male brain run between the front and the back of the same side of the brain, whereas in a typical female brain the connections are more likely to run from side to side between the left and right hemispheres of the brain. This goes along with earlier studies that indicated the Corpus Callosum, the largest band of horizontal connecting fibers in the brain, tends to be larger in the female brain.

Sleep Deprivation #6

Missing out on sleep can damage both your physical and emotional health. Jane  Brody, writer of a "Well" blog in the New York Times, has some suggestions.
1.  Engaging in physical activity (exercise) during the day can help you to fall asleep later on in the day. Because physical activity can increase your alertness, however, avoid exercising within 2-3 hours of  bedtime.
2. Managing anxiety and negative stress can help improve your sleep. Try taking a bath, relaxing your muscles, or meditating just before going to bed.
3. Making healthy choices about food and beverages can help improve the quality of your sleep. Avoid eating a big meal, drinking alcohol , or ingesting caffeine just before going to bed.
4. Consulting with your physician about prescription and over-the-counter drugs can result in medication changes that could improve your quality of sleep.
Each brain has an optimum sleep requirement. Make it a priority to figure out what your brain needs and then figure out how to give it what it needs.

Where Did The Sound Originate?

Can you tell where a sound is coming from? Identifying where a sound originated from isn't always an easy task, and it may become even more difficult as people age or develop hearing problems. New research published in the Journal of Neuroscience has found that a small group of neurons in the inferior colliculus (IC) are key to performing this task. The higher-level areas of the brain that actually determine what direction a sound comes from can't actually use the sound to solve the problem. Instead, these areas have to rely on how the sound was represented in electrical activity in lower-level auditory areas of the brain. In this work, the researchers recorded neural activity from the inferior colliculus in animals as they listened to sounds coming from various directions. The researchers found that they could figure out what direction the sound was coming from based on the pattern of activity from a collection of less than a hundred IC neurons. 
http://www.masseyeandear.org/news/press_releases/recent/decoding_sounds_source/