It refers to the neurons that live in the walls of your Enteric Nervous System or ENS. That’s another term for your Gastrointestinal (GI) Tract or gut. Its two-layered walls stretch from your esophagus to your rectum. Consensus used to be that neurons were relegated to the brain and spinal cord. Then researchers discovered ‘neurons’ in the ENS or GI system, counting perhaps a million or more. As equipment became more sophisticated, estimates were revised upwards to maybe 200-600 million. Recently I heard someone say that there may be as many neurons in your gut as in parts of your brain.
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