Using resting-state fMRI researchers observed brain circuity in adults with ADHD. Researchers linked increases in functional connectivity in specific brain regions to clinical symptoms of hyperactivity and restlessness, suggesting that inefficiencies in brain network processing could explain some symptoms of ADHD. Both male and female ADHD brains exhibit several brain differences when compared with non-ADHD brains. The overall brain size in children with ADHD tends to be smaller than the non-ADHD brains. The ADHD brain appears to mature more slowly than non-ADHD brains. Areas of the brain, such as the amygdala and hippocampus may have a smaller volume, as well, impacting how the individual brain processes and regulates emotions. Other brain regions, including the frontal lobes (especially the right frontal lobe), may also be smaller in volume, leading to inattention, impulsivity, and problems with social interactions.
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