ASD & Genetics, 2

The research of CSHL Associate Professor Ivan Lossifov and Professor Michael Wigler has shown that, in many cases, it’s the father who may be playing a bigger genetic role in the ASD of offspring. Researchers are not as yet certain of exactly how the father’s contribution to ASD occurs. Professor Lossifoy, however, has a couple of ideas. Lossifoy thinks that some fathers may carry protective mutations that fail to get passed on to the biological children. Or perhaps, fathers may pass down mutations that trigger the mother’s immune system to attack the developing embryo. Both theories offer hope for parents of children with ASD and other neurological disorders like schizophrenia. It also poses a question: could other disorders follow these same genetic rules? CSHL is continuing their research.

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