Electrophysiology,
although complicated, is one way to monitor activity of neurons. A team of
researchers from MIT has developed an instrument dubbed the Autopatcher that
has increased the success rate of this type of study. One of their goals is to obtain
whole-cell recordings from multiple neurons at one time. Of course this opens
up all manner of possibilities. As researcher Ed Boyden put it, “This opens up the
possibility of observing networks of cells interacting at the level of
individual neurons. We can eavesdrop on [cells] as they talk to each other, or
send one thing to a cell and see how it affects the next cell.” I started
thinking about what some of those conversations among neurons in my own brain
might be like—and started laughing out loud. Pay attention to your own internal
self-talk (neurons conversing with each other). What are they saying? If their
conversation isn’t helping you accomplish what you want to accomplish, tell
them what you want to have them talk about. Tell them how to say it. What fun!
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