Thursday, February 12, 2015
Genes and your Hippocampi
ENIGMA
researchers reported noticing genetic differences in the hippocampus (there are
two of them). The name hippocampus reportedly came from the fact that the shape of these little brain organs resemble that of a sea horse. They are linked to memory formation and organization (the hippocampi, not sea horses!) A gene sequence called
rs7294919 on chromosome #12 reportedly has been linked with variations in
hippocampus volume: Every instance of a genetic variant called a T-allele in
this region was linked to lower hippocampus volume equivalent to 3.9 years of
aging. (DNA is made up of four bases—A, C, T and G.) The location on the chromosome
(a threadlike structure that holds a DNA molecule) occurred between genes
associated with the regulation of cell death and with cellular brain
development and the cleaning up of proteins, including tau, which becomes
defective in Alzheimer's disease.
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