Kathleen Page and colleagues at the University of Southern
California, studied the effects of glucose and fructose on the hypothalamus—the
appetite control center, which responds to hormones such as Leptin that tell
the brain you are full (metaphorically think of leptin as the brake pedal). When study participants consumed a drink containing
only glucose, blood flow and activity in the hypothalamus decreased and they
reported feeling full. When the same participants were fed a fructose drink,
the hypothalamus remained active and they did not report feeling full. The
brain still thought the body was hungry.
(Gameau, Damon. The Sugar
Book. P. 121. NY:Flatiron Books, 2015)
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