A recent study led by Linda Mah MD, MHS was designed
to test the hypothesis that anxiety in individuals with amnestic mild cognitive
impairment (aMCI) can increase the rates of conversion to Alzheimer's disease
(AD). Amnestic Mild Cognitive Impairment (aMCI) is characterized by memory
impairment with preservation of functional independence and is considered a
transitional stage between normal aging and Alzheimer's disease (AD).However,
rates of conversion to AD are highly variable. Some 376 participants with aMCI
from the Alzheimer's Disease Neuroimaging Initiative (ADNI) were studied over a
median period of 36 months. The results of the study, published
in the American Journal of Geriatric Psychiatry reported that anxiety symptoms
in amnestic mild cognitive impairment are associated with medial temporal
atrophy and predict conversion to Alzheimer's disease.
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