In situations that involve anger, fear, trauma, crisis, or threat (anything that triggers a sense of helplessness) the brain automatically shifts its energy and attention from the neocortex to the reptilian brain in an attempt to access safety functions. When “downshifted,” the brain tends to experience a sense of anxiety rather than the excitement of a challenge, has difficulty problem-solving or recalling what it was told, and may suppress or interfere with immune system functions. Since your brain and immune system together constitute the most amazing healing system on this planet, downshifting can derail this system. Gratitude is the antidote for fear—information and knowledge can reinforce gratitude. If you look for it, there is always something for which to be thankful, which can upshift your brain and boost your immune system.