The Danish neuroscientist Maiken Nedergaard
coined the term Glymphatic System in recognition of its dependence upon glial
cells, along with the similarity of its functions to those of the body’s
peripheral lymphatic system. Two independent studies reportedly have shown that
the lymph vessels in the meninges (three layers of protective coverings) of the
brain, connect with the glymphatic system. When the glymphatic system is not
functioning properly insomnia is usually present. It appears that sleep
disturbances impact how this system operates. It also appears that sleep deprivation
can cause malfunctions in clearing the protein aggregates away, which has
implications for an increased risk of Alzheimer’s.
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