The actual main cause of Stiff person syndrome remains a medical mystery although research indicates that it is the result of an autoimmune response gone awry in the brain and spinal cord. It may be associated with diabetes, as well as other autoimmune diseases such as thyroiditis, vitiligo, and pernicious anemia. It may be misdiagnosed as Parkinson’s disease, multiple sclerosis, fibromyalgia, psychosomatic illness, or anxiety and phobia. Over time there may be an abnormal, hunched-over posture. Some individuals may be too disabled to walk or move. Many fall frequently because they do not have the normal reflexes to catch themselves, which can lead to serious injuries. People with SPS may be afraid to leave the house because street noises, such as the sound of a car horn, can trigger spasms and falls. The good news is that with accurate diagnosis and proper treatment, the symptoms of SPS may be controlled.
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