According to the National Human Genome Research Institute (genome.gov), the term human microbiome is typically used to describe the trillions of microorganisms—bacteria, viruses, fungi, and archaea (one-celled organisms without a cell nucleus)—that live on the skin, in the mouth, in the urogenital system, and in the gut. Your microbiome is dynamic, meaning that it can change for better or worse (e.g., ratio of desirable organisms getting out of balance with undesirable organisms) based on many environmental factors. These can include lifestyle choices such as exercise, food and beverage intake, medications, antibiotics, and other exposures.
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